Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241646 | 0.90 | MEN1 (0.46) | MEN1KMT2ACA2CA12CA1 | |
| SCHEMBL11243517 | 0.80 | PCTP (0.57) | KMT2ACA2CA1CA9NPC1 | |
| SCHEMBL11248363 | 0.79 | ATM (0.51) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL7605796 | 0.79 | MEN1 (0.50) | MEN1KMT2AATMCA2CA12 | |
| SCHEMBL8659039 | 0.78 | NPC1 (0.47) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL11235882 | 0.78 | ATM (0.46) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL11246999 | 0.78 | MEN1 (0.46) | MEN1KMT2AATMCYP2C9CYP3A4 | |
| SCHEMBL10908649 | 0.76 | NPC1 (0.45) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL9737605 | 0.76 | KMT2A (0.51) | MEN1KMT2AATMNPC1RAB9A | |
| SCHEMBL11390176 | 0.76 | ATM (0.45) | MEN1KMT2AATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |