Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241646 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11242119 | 0.83 | GCGR (0.53) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11245409 | 0.81 | MEN1 (0.47) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11242479 | 0.78 | MEN1 (0.46) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11245155 | 0.78 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11244669 | 0.77 | RORC (0.55) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10712873 | 0.76 | RAB9A (0.47) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8840271 | 0.76 | MEN1 (0.69) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8840302 | 0.76 | MEN1 (0.65) | MEN1KMT2AMAPTUSP2ALOX15 | |
| Diflubenzuron SCHEMBL42416 | 0.76 | RAB9A (0.59) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |