Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251656 | 0.88 | NOTUM (0.54) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL11253005 | 0.87 | NOTUM (0.53) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL11254979 | 0.87 | LMNA (0.47) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL11246007 | 0.84 | CHEK2 (0.35) | — | |
| SCHEMBL11256288 | 0.81 | NOTUM (0.40) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL11252856 | 0.80 | MMP2 (0.55) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL11247979 | 0.79 | SOS1 (0.38) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL31254967 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAHTTL3MBTL1 | |
| SCHEMBL11245574 | 0.77 | NT5E (0.41) | PTGES | |
| SCHEMBL11245732 | 0.77 | GUSB (0.45) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |