Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672523 | 0.76 | NAAA (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL12473809 | 0.74 | ALDH1A1 (0.46) | ALDH1A1POLBPKMCYP2C9CYP2D6 | |
| SCHEMBL9804356 | 0.73 | KMT2A (0.35) | ALDH1A1POLBPKMCYP2C9CYP1A2 | |
| SCHEMBL18428973 | 0.72 | ALDH1A1 (0.45) | ALDH1A1POLBPKMKMT2AMEN1 | |
| SCHEMBL28929645 | 0.71 | ALDH1A1 (0.49) | ALDH1A1POLBPKMCYP2C9CYP1A2 | |
| SCHEMBL5717885 | 0.70 | SIGMAR1 (0.45) | ALDH1A1POLBKMT2A | |
| SCHEMBL23142498 | 0.70 | ALDH1A1 (0.45) | ALDH1A1POLBPKMCYP2C9CYP1A2 | |
| SCHEMBL11243325 | 0.70 | GAA (0.38) | ALDH1A1POLBPKMCYP2C9CYP2D6 | |
| Hydrochloric Acid SCHEMBL5849112 | 0.69 | SIGMAR1 (0.44) | ALDH1A1POLBKMT2A | |
| SCHEMBL11711601 | 0.68 | NPSR1 (0.39) | ALDH1A1POLBPKMKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042170-A1 | A PROCESS FOR THE PREPARATION OF AZETIDINONES | BIOCHIMICA OPOS S.P.A. (IT) | 1997-11-13 | — | — | WO | disclosed |
| US-4775670-A | BACTERICIDES, ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4529698-A | Culturing Chromobacterium | E. R. SQUIBB & SONS, INC. (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0048096-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1982-03-24 | — | — | EP | disclosed |