Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244950 | 0.78 | PRMT6 (0.41) | PRMT6APEX1 | |
| SCHEMBL11247991 | 0.77 | KIF11 (0.40) | PRMT6HSD17B10APEX1KDM4EALDH1A1 | |
| SCHEMBL11254954 | 0.75 | ACHE (0.56) | CYP2C19HSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL11254944 | 0.75 | ACHE (0.56) | CYP2C19HSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL10741444 | 0.71 | PRMT6 (0.61) | PRMT6SOS1 | |
| SCHEMBL11460057 | 0.70 | PRMT6 (0.38) | PRMT6 | |
| SCHEMBL9870480 | 0.64 | CYP1A2 (0.46) | PRMT6CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL10846891 | 0.63 | PRMT6 (0.50) | PRMT6CYP1A2CYP2C19CYP2D6CYP3A4 | |
| SCHEMBL10743295 | 0.62 | PRMT6 (0.47) | PRMT6CYP1A2CYP2C19CYP2D6CYP3A4 | |
| Dimethylamine SCHEMBL9365842 | 0.62 | PRMT6 (0.57) | PRMT6CYP1A2CYP2C19HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001699-B1 | DERIVATIVES OF FURYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1982-02-24 | — | — | EP | disclosed |
| US-4288443-A | HISTAMINE ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1981-09-08 | — | — | US | disclosed |
| EP-0001699-A2 | Derivatives of furyl compounds, their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1979-05-02 | — | — | EP | disclosed |