Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733053 | 0.76 | PRMT6 (0.53) | PRMT6KDM4EHSD17B10ALDH1A1GAA | |
| SCHEMBL11254562 | 0.75 | KDM4E (0.61) | KDM4EMCL1KMT2AMEN1ERAP1 | |
| SCHEMBL9641616 | 0.74 | PRMT6 (0.51) | PRMT6KDM4EHSD17B10ALDH1A1GAA | |
| SCHEMBL10957232 | 0.74 | PRMT6 (0.59) | PRMT6APEX1 | |
| SCHEMBL11244950 | 0.74 | PRMT6 (0.41) | PRMT6APEX1L3MBTL1 | |
| SCHEMBL11247143 | 0.74 | BCHE (0.43) | KDM4E | |
| SCHEMBL11372301 | 0.73 | BCHE (0.36) | KDM4EKMT2AMEN1APEX1GLA | |
| SCHEMBL11253470 | 0.72 | ACHE (0.53) | KDM4EKMT2AMEN1HSD17B10TSHR | |
| SCHEMBL11243944 | 0.72 | SMN1; SMN2 (0.47) | KMT2APOLBALDH1A1HPGDNPSR1 | |
| SCHEMBL11253473 | 0.72 | ACHE (0.53) | KDM4EKMT2AMEN1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001699-B1 | DERIVATIVES OF FURYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1982-02-24 | — | — | EP | disclosed |
| US-4288443-A | HISTAMINE ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1981-09-08 | — | — | US | disclosed |