Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722376 | 0.79 | PDE5A (0.58) | PDE5AGUSBKDM4EPARP1ALDH1A1 | |
| SCHEMBL1960366 | 0.75 | TYMS (0.51) | TYMSALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1368260 | 0.72 | KDM4E (0.57) | PDE5AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29582392 | 0.72 | KDM4E (0.57) | PDE5AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7674037 | 0.72 | FGFR1 (0.52) | PDE5AGUSBKDM4EPARP1ALDH1A1 | |
| SCHEMBL31722934 | 0.71 | KDM4E (0.59) | PDE5AGUSBKDM4EALDH1A1MAPT | |
| SCHEMBL3111166 | 0.71 | KDM4E (0.59) | PDE5AGUSBKDM4EALDH1A1MAPT | |
| SCHEMBL6887071 | 0.70 | ALDH1A1 (0.52) | KDM4EPARP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8516383 | 0.70 | TSHR (0.52) | TYMSKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1839147 | 0.70 | L3MBTL1 (0.49) | TYMSKDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324682-A | PRESSURE RUPTURABLE; FOR MARKING AND IDENTIFICATION | AMERICAN CYANAMID COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4219438-A | Composition for marking and identification purposes | AMERICAN CYANAMID COMPANY (US) | 1980-08-26 | — | — | US | disclosed |
| US-3960755-A | Detecting compositions and method of using same | AMERICAN CYANAMID COMPANY (US) | 1976-06-01 | — | — | US | disclosed |