Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | GUSB | P08236 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MGAM | O43451 | 2/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31722934 | 1.00 | KDM4E (0.59) | KDM4EHPGDGUSBPDE5AGAA | |
| SCHEMBL11245430 | 0.84 | NPC1 (0.50) | KDM4EHPGDGUSBGAAALDH1A1 | |
| SCHEMBL5508220 | 0.83 | KDM4E (0.55) | KDM4EHPGDGUSBPDE5AGAA | |
| SCHEMBL2372869 | 0.83 | PTGES (0.51) | KDM4EHPGDGUSBPDE5AGAA | |
| SCHEMBL6887071 | 0.82 | ALDH1A1 (0.52) | KDM4EHPGDGAAALDH1A1NPC1 | |
| SCHEMBL8618622 | 0.81 | NPC1 (0.61) | KDM4EHPGDGAAMGAMSI | |
| SCHEMBL11332812 | 0.81 | NPC1 (0.61) | KDM4EHPGDGAAALDH1A1NPC1 | |
| SCHEMBL8623118 | 0.81 | PTGES (0.63) | KDM4EGUSBGAAMGAMSI | |
| SCHEMBL8618963 | 0.78 | ALDH1A1 (0.56) | KDM4EHPGDGUSBGAAALDH1A1 | |
| SCHEMBL15775502 | 0.77 | PARP1 (0.59) | GUSBGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313156-B1 | DISULFIDE-BASED PRODRUG COMPOUNDS | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2025-08-06 | — | — | EP | claimed |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-05-16 | — | — | US | claimed |
| EP-4320124-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2024-02-14 | — | — | EP | claimed |
| EP-4071148-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2022-10-12 | — | — | EP | claimed |
| EP-4062942-A1 | DISULFIDE-BASED PRODRUG COMPOUNDS | Ludwig-Maximilians-Universität München (DE) | 2022-09-28 | — | — | EP | claimed |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-11 | — | — | US | disclosed |
| EP-4313156-B1 | DISULFIDE-BASED PRODRUG COMPOUNDS | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2025-08-06 | — | — | EP | disclosed |
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-06-27 | — | — | US | disclosed |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2024-05-16 | — | — | US | disclosed |
| EP-4320124-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2024-02-14 | — | — | EP | disclosed |
| EP-4313156-A1 | DISULFIDE-BASED PRODRUG COMPOUNDS | Ludwig-Maximilians-Universität München (DE) | 2024-02-07 | — | — | EP | disclosed |
| US-20230075693-A1 | FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF | KURARAY NORITAKE DENTAL INC. (JP) | 2023-03-09 | — | — | US | disclosed |
| US-20070020715-A1 | Novel fluorogenic substrates for beta-lactamase gene expression | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-01-25 | — | — | US | disclosed |
| WO-2006085978-A2 | CONJUGATES OF A CEPHALOSPORIN DERIVATIVE AND A FLUOROPHOR PRECURSOR AND RELATED COMPOUNDS AS SUBSTRATES FOR BETA-LACTAMASE GENE EXPRESSION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-08-17 | — | — | WO | disclosed |
| US-20050181469-A1 | Beta-lactamase substrates having phenolic ethers | HOWARD HUGHES MEDICAL CENTER (US) | 2005-08-18 | — | — | US | disclosed |
| US-20050118669-A1 | Novel fluorogenic substrates for beta-lactamase gene expression | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-06-02 | — | — | US | disclosed |
| EP-1385853-A4 | BETA-LACTAMASE SUBSTRATES HAVING PHENOLIC ETHERS | UNIV CALIFORNIA (US) | 2005-02-16 | — | — | EP | disclosed |
| EP-1385853-A2 | Beta-lactamase substrates having phenolic ethers | The Regents of the University of California (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20030003526-A1 | Beta-lactamase substrates having phenolic ethers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-02 | — | — | US | disclosed |
| WO-2002068678-A2 | BETA-LACTAMASE SUBSTRATES HAVING PHENOLIC ETHERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | BRD1, TBCA, BAZ1A | KDM4E 1086/4885HPGD 1308/4885GUSB 1835/4885 |
| US-20050181469-A1 | Beta-lactamase substrates having phenolic ethers | DBH, CMBL, NCEH1 | KDM4E 352/4885HPGD 2588/4885GUSB 35/4885 |
| US-20070020715-A1 | Novel fluorogenic substrates for beta-lactamase gene expression | CMBL, HRH3, TDO2 | KDM4E 1516/4885HPGD 2638/4885GUSB 122/4885 |
| US-20050118669-A1 | Novel fluorogenic substrates for beta-lactamase gene expression | CMBL, GLB1, SMYD2 | KDM4E 455/4885HPGD 2076/4885GUSB 32/4885 |
| US-20240207414-A1 | DISULFIDE-BASED PRODRUG COMPOUND | CBS, MSR1, P4HB | KDM4E 4718/4885HPGD 281/4885GUSB 162/4885 |
| US-20240156965-A1 | DICHALCOGENIDE PRODRUGS | DHCR7, DECR1, CYP27A1 | KDM4E 4690/4885HPGD 483/4885GUSB 58/4885 |
| US-20030003526-A1 | Beta-lactamase substrates having phenolic ethers | CMBL, GLB1, MGAM2 | KDM4E 855/4885HPGD 2583/4885GUSB 37/4885 |
| US-20230075693-A1 | FLUORESCENT CURABLE DENTAL COMPOSITION AND CURED PRODUCT THEREOF | BRD1, TBCA, BAZ1A | KDM4E 1086/4885HPGD 1308/4885GUSB 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.