Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920475 | 0.82 | MEN1 (0.41) | MEN1KMT2AGAAALDH1A1ADORA2B | |
| SCHEMBL11233534 | 0.73 | TP53 (0.36) | KMT2A | |
| SCHEMBL10898552 | 0.72 | ADORA2B (0.39) | MEN1KMT2AGAAALDH1A1ADORA2B | |
| SCHEMBL10898786 | 0.72 | ADORA2B (0.39) | MEN1KMT2AGAAALDH1A1ADORA2B | |
| SCHEMBL11243181 | 0.71 | ADORA2B (0.33) | ALDH1A1ADORA2B | |
| SCHEMBL11245438 | 0.71 | TP53 (0.34) | — | |
| SCHEMBL11235283 | 0.69 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1ADORA2BPOLB | |
| SCHEMBL10918331 | 0.69 | MAPT (0.37) | ADORA2B | |
| SCHEMBL11230853 | 0.69 | ADORA2B (0.37) | MEN1KMT2AGAAALDH1A1ADORA2B | |
| SCHEMBL11236134 | 0.68 | ALDH1A1 (0.43) | MEN1KMT2AGAAALDH1A1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |