Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245438 | 0.87 | TP53 (0.34) | TP53 | |
| SCHEMBL15413590 | 0.86 | TP53 (0.33) | TP53 | |
| SCHEMBL11250408 | 0.86 | ALDH1A1 (0.40) | TP53KMT2A | |
| SCHEMBL11240899 | 0.84 | ALDH1A1 (0.38) | TP53 | |
| SCHEMBL11243781 | 0.81 | TP53 (0.37) | TP53KMT2A | |
| SCHEMBL11243898 | 0.81 | LMNA (0.35) | TP53KMT2A | |
| SCHEMBL11243254 | 0.79 | TDP1 (0.38) | KMT2A | |
| SCHEMBL11248743 | 0.78 | HSD17B10 (0.37) | KMT2A | |
| SCHEMBL11235707 | 0.78 | TP53 (0.35) | TP53KMT2A | |
| SCHEMBL11245890 | 0.73 | MEN1 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148292-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2015-05-28 | — | — | US | claimed |
| WO-2014011540-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2014-01-16 | — | — | WO | claimed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-10933169-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | EMORY UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
| US-10434220-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | EMORY UNIVERSITY (US) | 2019-10-08 | — | — | US | disclosed |
| US-20160089478-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2016-03-31 | — | — | US | disclosed |
| US-20150148292-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2015-05-28 | — | — | US | disclosed |
| US-20150148292-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2015-05-28 | — | — | US | disclosed |
| WO-2014011540-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2014-01-16 | — | — | WO | disclosed |
| WO-2014011540-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2014-01-16 | — | — | WO | disclosed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148292-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | BMP4, BMP2, BMP1 | TP53 1749/4885KMT2A 4390/4885 |
| US-10434220-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | BMP2, BMP4, BMP1 | TP53 2455/4885KMT2A 3326/4885 |
| US-10933169-B2 | Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto | BMP2, BMP4, BMP1 | TP53 2455/4885KMT2A 3326/4885 |
| US-20160089478-A1 | BONE MORPHOGENETIC PROTEIN PATHWAY ACTIVATION, COMPOSITIONS FOR OSSIFICATION, AND METHODS RELATED THERETO | BMP2, BMP4, BMP1 | TP53 2455/4885KMT2A 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.