Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23445600 | 0.80 | RNASEH1 (0.49) | KMT2ARNASEH1HTR2CHTR2BHTR2A | |
| SCHEMBL28922579 | 0.79 | HTR2C (0.49) | KMT2ARNASEH1HTR2CHTR2BHTR2A | |
| SCHEMBL3739629 | 0.73 | AADAT (0.44) | KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL8784223 | 0.72 | KMT2A (0.50) | KMT2AACHETSHRKDM4EALDH1A1 | |
| SCHEMBL7238441 | 0.72 | HTR2C (0.46) | HTR2CHTR2BHTR2ASMN1; SMN2TSHR | |
| SCHEMBL2461097 | 0.71 | KMT2A (0.63) | KMT2ARNASEH1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL31019490 | 0.71 | KMT2A (0.63) | KMT2ARNASEH1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL13587856 | 0.70 | CAPN1 (0.39) | KMT2ARNASEH1HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL3748099 | 0.69 | KMT2A (0.61) | KMT2ARNASEH1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL31019547 | 0.68 | BCAT2 (0.50) | KMT2ARNASEH1HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313950-A | Antireproductive tricyclic ortho-fused nitrogen containing compounds | GRUPPO LEPETIT S.P.A. (IT) | 1982-02-02 | — | — | US | disclosed |
| US-4275066-A | 1,2,4-TRIAZOLO(5.1A)ISOINDOZE, TRIAZOLO(5.1A) ISOQUINOLINE OR 1,2,4,-TRIAZOLO (5.1A)(2) BENZAZEPINE CONTRACEPTIVES | GRUPPO LEPETIT S.P.A. (IT) | 1981-06-23 | — | — | US | disclosed |