Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256846 | 0.89 | NR2F2 (0.59) | SMN1; SMN2LMNARAB9ANPC1NR2F2 | |
| SCHEMBL11250025 | 0.88 | NPC1 (0.52) | SMN1; SMN2RAB9ANPC1NR2F2KMT2A | |
| SCHEMBL11248882 | 0.86 | EGFR (0.52) | SMN1; SMN2RAB9ANPC1NR2F2KMT2A | |
| SCHEMBL11255628 | 0.86 | GBA1 (0.56) | SMN1; SMN2LMNARAB9ANPC1NR2F2 | |
| SCHEMBL11245261 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2S1PR2LMNANPSR1RAB9A | |
| SCHEMBL11254153 | 0.83 | LDHA (0.61) | SMN1; SMN2S1PR2LMNANPSR1RAB9A | |
| SCHEMBL11240075 | 0.80 | EGFR (0.53) | SMN1; SMN2LMNANPSR1RAB9ANPC1 | |
| SCHEMBL11261278 | 0.79 | EGFR (0.52) | SMN1; SMN2LMNARAB9ANPC1NR2F2 | |
| SCHEMBL4572178 | 0.79 | GALR3 (0.63) | SMN1; SMN2S1PR2LMNANPSR1RAB9A | |
| SCHEMBL13283199 | 0.79 | GALR3 (0.63) | SMN1; SMN2S1PR2LMNANPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |