Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276461 | 0.75 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL9754384 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL4074628 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL492025 | 0.71 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL11536638 | 0.70 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| Hydrochloric Acid SCHEMBL4180695 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL25148779 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL4429820 | 0.69 | KDM4E (0.93) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL9754429 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 | |
| SCHEMBL11734390 | 0.67 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2GAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315014-A | Antibacterial amide compounds and pharmaceutical composition containing the same | WARNER-LAMBERT COMPANY (US) | 1982-02-09 | — | — | US | disclosed |