Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OGG1 | O15527 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251379 | 0.81 | CYP1A2 (0.36) | HTTTSHRALDH1A1MAPTKMT2A | |
| SCHEMBL11092487 | 0.81 | LMNA (0.37) | HTTTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11256689 | 0.81 | CRBN (0.31) | POLBCYP1A2 | |
| SCHEMBL11252255 | 0.81 | HTT (0.40) | HTTTSHRALDH1A1AKT1LMNA | |
| SCHEMBL11248653 | 0.81 | HTT (0.55) | HTTTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11096378 | 0.81 | RAPGEF4 (0.42) | HTTTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11259523 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAKMT2APOLB | |
| SCHEMBL11086646 | 0.78 | HTT (0.44) | HTTTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11266319 | 0.78 | HTT (0.39) | HTTTSHRALDH1A1MAPTLMNA | |
| SCHEMBL11259908 | 0.78 | CYP1A2 (0.36) | ALDH1A1MAPTKMT2APOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4115564-A | Treatment of diarrhea with amidinoureas | WILLIAM H. RORER, INC. (US) | 1978-09-19 | — | — | US | disclosed |