Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548343 | 0.74 | LMNA (0.39) | LMNACYP2C9HSD17B10 | |
| SCHEMBL5194656 | 0.74 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2OPRM1OPRD1 | |
| SCHEMBL11236719 | 0.73 | DRD2 (0.53) | SLC6A4SLC6A3SLC6A2LMNAOPRM1 | |
| SCHEMBL11173936 | 0.73 | OPRL1 (0.60) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL11173935 | 0.73 | OPRL1 (0.60) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL13933070 | 0.72 | CYP2C9 (0.50) | LMNACYP2C9 | |
| SCHEMBL6698945 | 0.72 | CES1 (0.46) | LMNAHSD17B10 | |
| SCHEMBL11341980 | 0.72 | CES1 (0.46) | LMNAHSD17B10 | |
| SCHEMBL28433377 | 0.72 | LMNA (0.50) | LMNAHSD17B10 | |
| SCHEMBL29516310 | 0.71 | HTR3E (0.56) | HTR3EHTR3BCHRNA7HTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | disclosed |