Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247772 | 0.83 | GAA (0.45) | TSHRPOLBCYP2C19GLAMAPT | |
| SCHEMBL11264343 | 0.82 | POLB (0.41) | TDP1TSHRPTGDR2POLBSMN1; SMN2 | |
| SCHEMBL18780289 | 0.66 | KDM4E (0.49) | TDP1TSHRPTGDR2POLBSMN1; SMN2 | |
| SCHEMBL18780641 | 0.66 | TDP1 (0.59) | TDP1TSHRPTGDR2POLBSMN1; SMN2 | |
| SCHEMBL11258085 | 0.66 | ALDH1A1 (0.44) | TSHRPOLBSMN1; SMN2CYP2C19GLA | |
| SCHEMBL5070268 | 0.65 | RAB9A (0.56) | PTGDR2CYP2C19L3MBTL1MAPTKDM4E | |
| SCHEMBL8846694 | 0.65 | L3MBTL1 (0.56) | TSHRPOLBSMN1; SMN2L3MBTL1MCL1 | |
| SCHEMBL11269013 | 0.64 | L3MBTL1 (0.45) | TDP1CYP2C19L3MBTL1MAPT | |
| SCHEMBL5065516 | 0.64 | SMN1; SMN2 (0.46) | TDP1PTGDR2POLBSMN1; SMN2GLA | |
| SCHEMBL320418 | 0.63 | PTGDR2 (0.66) | TDP1TSHRPTGDR2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324892-A | 7-(N-Substituted-2-phenylglycinamido)-3-substituted-3-cephem-4-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-13 | — | — | US | disclosed |
| US-4172198-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-10-23 | — | — | US | disclosed |