Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 8/20 | 0.48 |
| ▸ | HRH2 | P25021 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248409 | 0.82 | ALDH1A1 (0.54) | MEN1ALDH1A1POLBKMT2ACYP1A2 | |
| SCHEMBL11243418 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2AHRH3CYP1A2 | |
| SCHEMBL7293790 | 0.78 | GAA (0.58) | ALDH1A1POLBKMT2ATBXAS1CYP1A2 | |
| SCHEMBL7855826 | 0.76 | LMNA (0.59) | KMT2ACYP19A1LMNAL3MBTL1 | |
| SCHEMBL23657179 | 0.75 | ALDH1A1 (0.65) | ALDH1A1POLBKMT2ACYP19A1HTT | |
| SCHEMBL11247290 | 0.75 | NPSR1 (0.55) | ALDH1A1POLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL11142733 | 0.74 | TBXAS1 (0.51) | ALDH1A1POLBKMT2ATBXAS1LMNA | |
| SCHEMBL17629967 | 0.74 | ALDH1A1 (0.45) | MEN1ALDH1A1POLBKMT2ACYP1A2 | |
| SCHEMBL27090339 | 0.74 | ALDH1A1 (0.80) | ALDH1A1POLBKMT2ALMNAHTT | |
| SCHEMBL25009512 | 0.74 | ALDH1A1 (0.80) | ALDH1A1POLBKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504574-B1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | WAKAMOTO PHARMA CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5356916-A | Treating Parkinson*s disease | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0504574-A1 | 1,2,4-Oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity and method for preparing same | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1992-09-23 | — | — | EP | disclosed |