SCHEMBL11248544

SCHEMBL11248544

[Al]OC(Cc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
SLC6A2 P23975 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
KIF11 P52732 1/20 0.39
KCNA5 P22460 1/20 0.38
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.36
TSHR P16473 1/20 0.36
FDPS P14324 1/20 0.35
CALM1 P0DP23 1/20 0.35
CYP3A4 P08684 2/20 0.34
RECQL P46063 1/20 0.34
KCNH2 Q12809 2/20 0.34
OPRM1 P35372 2/20 0.34
OPRD1 P41143 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7001871 0.82 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL765190 0.78 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL5145585 0.78 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL9614595 0.78 CYP1A2 (0.54) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL238218 0.78 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL4454996 0.77 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL5145593 0.75 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL23633166 0.74 CYP1A2 (0.44) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL2484068 0.74 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19KIF11KCNA5
SCHEMBL11122216 0.74 FDPS (0.44) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4357319-A INSECTICIDES, ATTRACTANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-11-02 US disclosed
US-4328206-A Method of attracting and destroying tobacco beetles with alkyl phenethylethers INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-05-04 US disclosed