Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 9/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212810 | 0.71 | CA2 (0.50) | PDE3BPDE3AALDH1A1HPGDMAPT | |
| SCHEMBL4649359 | 0.69 | PDE3B (0.71) | PDE3BPDE3AGPR119PDE4APDE4B | |
| SCHEMBL11248796 | 0.66 | PDE3B (0.42) | PDE3BPDE3AALDH1A1HPGDGPR119 | |
| SCHEMBL7305470 | 0.60 | KDM4E (0.41) | ALDH1A1HPGDMAPTGPR119HTT | |
| SCHEMBL11146386 | 0.60 | AXL (0.44) | PDE3BPDE3AALDH1A1HPGDMAPT | |
| SCHEMBL13400655 | 0.58 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTGPR119HTT | |
| SCHEMBL13400652 | 0.58 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTGPR119HTT | |
| SCHEMBL7355279 | 0.57 | CHRNB4 (0.53) | CHRNB4CHRNA3 | |
| SCHEMBL2804521 | 0.57 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPTHTTL3MBTL1 | |
| SCHEMBL8871280 | 0.56 | KDM4E (0.46) | PDE3BPDE3AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334030-A | INJECTION MOLDABLE CONCENTRATES CONTAINING AMIDE DERIVATIVES OF AZODICARBOXYLIC ACID AND A DIHYDROOXADIAZINONE AS BLOWING AGENTS | GENERAL ELECTRIC COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4163037-A | USING A DIHYDROOXADIAZINONE BLOWING AGENT, INJECTION MOLDING | GENERAL ELECTRIC COMPANY (US) | 1979-07-31 | — | — | US | disclosed |
| US-4097425-A | POLYCARBONATES, POLYESTERS, SUBSTITUTED 3,6-DIHYDRO-1,3,4-OXDIAZIN-2-ONE | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |