Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649359 | 0.67 | PDE3B (0.71) | PDE3BPDE3AGPR119 | |
| SCHEMBL11248792 | 0.66 | PDE3B (0.38) | PDE3BPDE3AGPR119KDM4EALDH1A1 | |
| SCHEMBL212810 | 0.66 | CA2 (0.50) | PDE3BPDE3AGPR119SMN1; SMN2KDM4E | |
| SCHEMBL29123410 | 0.62 | MAOB (0.36) | SMN1; SMN2MDM2KDM4EALDH1A1HPGD | |
| SCHEMBL5583922 | 0.62 | HPGD (0.48) | SMN1; SMN2KDM4EALDH1A1HPGDCTSB | |
| SCHEMBL2154210 | 0.61 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL7329283 | 0.60 | TSHR (0.41) | SMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL6508006 | 0.60 | TSHR (0.41) | SMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL7331133 | 0.60 | TSHR (0.41) | SMN1; SMN2ALDH1A1HSD11B1 | |
| SCHEMBL11114725 | 0.59 | TAAR1 (0.50) | SMN1; SMN2KDM4EALDH1A1BRD4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334030-A | INJECTION MOLDABLE CONCENTRATES CONTAINING AMIDE DERIVATIVES OF AZODICARBOXYLIC ACID AND A DIHYDROOXADIAZINONE AS BLOWING AGENTS | GENERAL ELECTRIC COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4163037-A | USING A DIHYDROOXADIAZINONE BLOWING AGENT, INJECTION MOLDING | GENERAL ELECTRIC COMPANY (US) | 1979-07-31 | — | — | US | disclosed |
| US-4097425-A | POLYCARBONATES, POLYESTERS, SUBSTITUTED 3,6-DIHYDRO-1,3,4-OXDIAZIN-2-ONE | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |