Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568139 | 0.84 | NPY5R (0.50) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL28259164 | 0.81 | ALDH1A1 (0.45) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL20029880 | 0.81 | NOD2 (0.43) | GAATRPM8ALDH1A1HPGDPGR | |
| SCHEMBL14008052 | 0.81 | NPY5R (0.52) | ADRA2CHPGDADRA2AADRA2BHTR2A | |
| SCHEMBL8615898 | 0.81 | NPY5R (0.52) | ADRA2CHPGDADRA2AADRA2BHTR2A | |
| SCHEMBL14008053 | 0.81 | NPY5R (0.52) | ADRA2CHPGDADRA2AADRA2BHTR2A | |
| SCHEMBL18320604 | 0.79 | PGR (0.44) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL394512 | 0.79 | HSD11B1 (0.53) | TRPM8ALDH1A1HPGDPGRADRA2A | |
| SCHEMBL3057264 | 0.78 | ALPI (0.44) | GAAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL3644875 | 0.78 | MEN1 (0.59) | GAAALDH1A1KCNH2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341893-A | HYPOTENSIVE AGENTS | SYNTHELABO (FR) | 1982-07-27 | — | — | US | disclosed |