Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263661 | 0.88 | RAB9A (0.33) | KMT2APKMALDH1A1NPC1RAB9A | |
| SCHEMBL11264271 | 0.88 | RAB9A (0.41) | KMT2APKMALDH1A1RAB9AMAPT | |
| SCHEMBL11247393 | 0.87 | KDM4E (0.35) | KMT2APKMALDH1A1RAB9ATSHR | |
| SCHEMBL11264814 | 0.86 | KMT2A (0.40) | KMT2APKMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11254919 | 0.84 | RAB9A (0.49) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11267977 | 0.80 | MEN1 (0.34) | KMT2APKMALDH1A1TSHRMAPT | |
| SCHEMBL11246682 | 0.79 | GDA (0.33) | KMT2APKMALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11127952 | 0.78 | MEN1 (0.37) | KMT2APKMALDH1A1TSHRMAPT | |
| SCHEMBL26343319 | 0.77 | ALDH1A1 (0.44) | KMT2APKMALDH1A1PTPN2PTPN1 | |
| SCHEMBL11394276 | 0.77 | KMT2A (0.50) | KMT2APKMALDH1A1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028936-A2 | 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-20 | — | — | EP | claimed |
| US-4332806-A | Antitumor and immunosuppresive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0028936-A2 | 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-20 | — | — | EP | disclosed |