Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127952 | 0.89 | MEN1 (0.37) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11264271 | 0.85 | RAB9A (0.41) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11247393 | 0.85 | KDM4E (0.35) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11085470 | 0.84 | THRB (0.39) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11264814 | 0.84 | KMT2A (0.40) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11263661 | 0.83 | RAB9A (0.33) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11129141 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11265126 | 0.83 | LMNA (0.39) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11395198 | 0.83 | GAA (0.46) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL11130743 | 0.82 | GDA (0.35) | MEN1KMT2AKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028936-A2 | 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-20 | — | — | EP | claimed |
| US-4332806-A | Antitumor and immunosuppresive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0028936-A2 | 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-20 | — | — | EP | disclosed |