Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129141 | 0.83 | ALDH1A1 (0.39) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11265126 | 0.83 | LMNA (0.39) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11395198 | 0.83 | GAA (0.46) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11130743 | 0.82 | GDA (0.35) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11085470 | 0.82 | THRB (0.39) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11254919 | 0.81 | RAB9A (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11127952 | 0.81 | MEN1 (0.37) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11130851 | 0.80 | GDA (0.33) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11267977 | 0.79 | MEN1 (0.34) | GDAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11249248 | 0.79 | KMT2A (0.35) | MEN1KMT2AALDH1A1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332806-A | Antitumor and immunosuppresive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0028936-A2 | 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-20 | — | — | EP | disclosed |