Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264814 | 0.91 | KMT2A (0.40) | MEN1KMT2AALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11263661 | 0.91 | RAB9A (0.33) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11247393 | 0.91 | KDM4E (0.35) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11249248 | 0.88 | KMT2A (0.35) | RAB9AMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11267977 | 0.85 | MEN1 (0.34) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL11127952 | 0.83 | MEN1 (0.37) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL11261625 | 0.83 | MEN1 (0.52) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL11265126 | 0.78 | LMNA (0.39) | MEN1KMT2AALDH1A1KDM4EATM | |
| SCHEMBL11129141 | 0.78 | ALDH1A1 (0.39) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11395198 | 0.77 | GAA (0.46) | RAB9AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332806-A | Antitumor and immunosuppresive 4-carbamoyl imidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0028936-A2 | 4-Carbamoylimidazol-5-ol derivatives, their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-05-20 | — | — | EP | disclosed |