Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255619 | 0.83 | LMNA (0.36) | LRRK2SMN1; SMN2SCN9ACYP17A1LMNA | |
| SCHEMBL11263093 | 0.81 | TDO2 (0.41) | KCNA5L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL11248931 | 0.81 | TDO2 (0.44) | CRHR1GRIA1CACNG8LMNAHPGD | |
| SCHEMBL11262924 | 0.80 | HPGD (0.36) | L3MBTL1LMNAPOLBMAPTHPGD | |
| SCHEMBL11258381 | 0.78 | TDP1 (0.48) | DPP4KCNA5MAPTNR4A2 | |
| SCHEMBL10392251 | 0.77 | CYP2A6 (0.52) | DPP4GRIA1CACNG8POLBMAPT | |
| SCHEMBL11251011 | 0.75 | BCHE (0.44) | SMN1; SMN2MAPK14CYP17A1GAABCHE | |
| SCHEMBL11261674 | 0.75 | TDO2 (0.36) | SMN1; SMN2GPR84NPSR1 | |
| SCHEMBL11253084 | 0.75 | ALDH1A1 (0.36) | SMN1; SMN2L3MBTL1LMNAPOLBMAPT | |
| SCHEMBL21617927 | 0.73 | ALDH1A1 (0.45) | SMN1; SMN2GRIA1CACNG8MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |