Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13525226 | 0.87 | PGK1 (0.37) | PGK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL11410488 | 0.83 | PTGS1 (0.36) | CA1CA2CA9ALDH1A1ROCK2 | |
| SCHEMBL10783938 | 0.82 | ALDH1A1 (0.33) | CA1CA2CA9ALDH1A1ROCK2 | |
| SCHEMBL12332823 | 0.82 | ADRA2A (0.38) | ALDH1A1KMT2ALMNAMEN1MAPT | |
| SCHEMBL11321392 | 0.81 | PABPC1 (0.34) | ALDH1A1 | |
| SCHEMBL11410525 | 0.81 | ABCB11 (0.31) | ALDH1A1 | |
| SCHEMBL11248717 | 0.79 | HTT (0.33) | ALDH1A1MAPT | |
| SCHEMBL11256805 | 0.78 | KDM4E (0.33) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL11410522 | 0.78 | MAPT (0.44) | CA1CA2CA9ALDH1A1KMT2A | |
| SCHEMBL10784128 | 0.77 | NPC1 (0.36) | ALDH1A1KMT2ALMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361516-A | N-Monosubstituted indoanilines | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-11-30 | — | — | US | claimed |
| US-4184844-A | Storage stable indoaniline and indophenol dye solutions, a process for producing the same and hair dye compositions containing the same | L'OREAL (FR) | 1980-01-22 | — | — | US | disclosed |