Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269712 | 0.87 | CYP1A2 (0.34) | — | |
| SCHEMBL11473003 | 0.81 | ADORA3 (0.35) | HTTPDPK1 | |
| SCHEMBL11471657 | 0.78 | GLA (0.36) | ALDH1A1POLB | |
| SCHEMBL11473449 | 0.77 | TSHR (0.38) | POLBMAPT | |
| SCHEMBL11472946 | 0.75 | GPR84 (0.43) | ALDH1A1LMNA | |
| SCHEMBL11261620 | 0.75 | HSD17B10 (0.38) | ALDH1A1POLBMAPT | |
| SCHEMBL11480703 | 0.73 | GPR84 (0.50) | ALDH1A1MAPT | |
| SCHEMBL11478282 | 0.73 | RNASEH1 (0.58) | MAPT | |
| SCHEMBL11480985 | 0.71 | CHEK2 (0.43) | MAPTLMNA | |
| SCHEMBL10705902 | 0.68 | LMNA (0.41) | LMNAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003265-B1 | IMMUNOSTIMULATORY IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-17 | — | — | EP | disclosed |
| US-4209525-A | IMMUNOSTIMULANT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-06-24 | — | — | US | disclosed |
| EP-0003265-A1 | Immunostimulatory imidazole derivatives, their preparation and their pharmaceutical compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-08-08 | — | — | EP | disclosed |