SCHEMBL11269712

SCHEMBL11269712

NC(=O)c1nc(CC(=O)O)[nH]c1O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
DGAT1 O75907 1/20 0.34
RNASEH1 O60930 1/20 0.30
HSD17B10 Q99714 2/20 0.30
CYP2C19 P33261 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11253236 0.87 ALDH1A1 (0.34)
SCHEMBL11473003 0.79 ADORA3 (0.35)
SCHEMBL11471657 0.76 GLA (0.36) RNASEH1HSD17B10
SCHEMBL11473449 0.75 TSHR (0.38) HSD17B10
SCHEMBL11478282 0.75 RNASEH1 (0.58) RNASEH1
SCHEMBL11472946 0.74 GPR84 (0.43)
SCHEMBL11480703 0.71 GPR84 (0.50)
SCHEMBL10705902 0.71 LMNA (0.41) HSD17B10
SCHEMBL11472422 0.66 NPSR1 (0.45) RNASEH1
SCHEMBL11479983 0.64 PIN1 (0.56) CYP1A2RNASEH1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003265-B1 IMMUNOSTIMULATORY IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-03-17 EP disclosed
US-4209525-A IMMUNOSTIMULANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-06-24 US disclosed
EP-0003265-A1 Immunostimulatory imidazole derivatives, their preparation and their pharmaceutical compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-08-08 EP disclosed