Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050707 | 0.88 | KMT2A (0.52) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11054990 | 0.87 | TBXA2R (0.47) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11054953 | 0.87 | TBXA2R (0.44) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11052550 | 0.87 | GAA (0.51) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11052090 | 0.87 | MAPT (0.54) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11053862 | 0.85 | ALDH1A1 (0.48) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11049847 | 0.85 | PKM (0.60) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11054066 | 0.84 | TBXA2R (0.42) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11263800 | 0.82 | HTT (0.59) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11049969 | 0.82 | MEN1 (0.50) | MAPTALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |