Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255648 | 1.00 | RAB9A (0.35) | RAB9AMEN1GFERKMT2ANPC1 | |
| SCHEMBL11184749 | 0.78 | NOS3 (0.37) | KMT2ASMN1; SMN2SIGMAR1MAPTAPOBEC3A | |
| SCHEMBL11184751 | 0.78 | NOS3 (0.37) | KMT2ASMN1; SMN2SIGMAR1MAPTAPOBEC3A | |
| SCHEMBL11182662 | 0.77 | NISCH (0.39) | RAB9ANPC1CYP2D6 | |
| SCHEMBL11184346 | 0.75 | SPHK1 (0.41) | CYP2D6 | |
| SCHEMBL11368555 | 0.69 | PKM (0.37) | RAB9AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11364497 | 0.69 | PKM (0.37) | RAB9AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10916288 | 0.68 | ALDH1A1 (0.38) | RAB9AMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10916286 | 0.68 | ALDH1A1 (0.38) | RAB9AMEN1KMT2ASMN1; SMN2MAPT | |
| Bromide SCHEMBL10832877 | 0.67 | ALDH1A1 (0.37) | RAB9AMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001663-B1 | NOVEL 2-ARYLAMINO-HEXAHYDROPYRIMIDINES AND -IMIDAZOLIDINES, SALTS AND COMPLEXES THEREOF, METHOD OF PREPARING THE NOVEL COMPOUNDS AND FUNGICIDAL COMPOSITIONS WHICH CONTAIN THE NOVEL COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-05-12 | — | — | EP | disclosed |