Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259613 | 0.92 | HRH1 (0.49) | SLC6A2SLC6A4SLC6A3HRH1HTR1B | |
| SCHEMBL11260050 | 0.87 | TAAR1 (0.62) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL11260586 | 0.83 | DRD2 (0.58) | DRD2DRD1DRD4DRD5HTR7 | |
| SCHEMBL11250748 | 0.80 | HRH1 (0.60) | DRD2DRD1DRD4DRD5TAAR1 | |
| SCHEMBL11245170 | 0.80 | DRD2 (0.55) | DRD2DRD1DRD4DRD5SLC6A2 | |
| SCHEMBL11264682 | 0.79 | TAAR1 (0.58) | DRD2DRD1DRD4DRD5TAAR1 | |
| SCHEMBL11257616 | 0.78 | HTR7 (0.66) | DRD2DRD1DRD4DRD5HTR7 | |
| Hydrochloric Acid SCHEMBL11258745 | 0.78 | TAAR1 (0.57) | TAAR1HRH1HTR1B | |
| SCHEMBL11269198 | 0.78 | TAAR1 (0.57) | DRD2DRD1DRD4DRD5TAAR1 | |
| SCHEMBL11244476 | 0.77 | DRD2 (0.74) | DRD2DRD1DRD4DRD5HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |