Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 10/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882293 | 0.86 | LMNA (0.39) | VCAM1HMGCRPTGS1CYP1A2CYP2D6 | |
| SCHEMBL8859110 | 0.86 | VCAM1 (0.41) | VCAM1HMGCRCYP1A2CYP2D6LMNA | |
| SCHEMBL3424148 | 0.85 | ESR1 (0.43) | VCAM1HMGCRLMNARECQLGAA | |
| SCHEMBL11240651 | 0.85 | VCAM1 (0.40) | VCAM1HMGCRPTGS1LMNARECQL | |
| SCHEMBL1070390 | 0.83 | HMGCR (0.42) | VCAM1HMGCRCYP1A2CYP2D6LMNA | |
| SCHEMBL380043 | 0.82 | GPR55 (0.38) | VCAM1HMGCRCYP1A2CYP2D6LMNA | |
| SCHEMBL9705163 | 0.82 | ESR1 (0.43) | — | |
| SCHEMBL4595779 | 0.80 | VCAM1 (0.47) | VCAM1HMGCRPTGS1CYP1A2CYP2D6 | |
| SCHEMBL3949802 | 0.78 | ALDH1A1 (0.42) | VCAM1HMGCRPTGS1CYP1A2CYP2D6 | |
| SCHEMBL11490738 | 0.76 | VCAM1 (0.39) | VCAM1CYP1A2LMNARECQLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341879-A | Polyphenylene ether resin composition having improved heat stability and impact strength | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-07-27 | — | — | US | disclosed |