Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705431 | 0.85 | HTT (0.54) | HTTFOLH1CTRB1CASP1MME | |
| SCHEMBL6806205 | 0.85 | HTT (0.56) | HTTFOLH1CTRB1CASP1MME | |
| SCHEMBL20820039 | 0.84 | CASP1 (0.58) | HTTCTRB1CASP1ATMCTSL | |
| SCHEMBL8061660 | 0.84 | ATM (0.56) | HTTFOLH1CTRB1ATMCTSL | |
| SCHEMBL265604 | 0.84 | ATM (0.56) | HTTFOLH1CTRB1ATMCTSL | |
| SCHEMBL7624700 | 0.84 | FOLH1 (0.59) | HTTFOLH1CTRB1CASP1MME | |
| SCHEMBL2921260 | 0.84 | FOLH1 (0.59) | HTTFOLH1CTRB1CASP1MME | |
| SCHEMBL910423 | 0.84 | FOLH1 (0.70) | FOLH1CASP1MMEECE1 | |
| SCHEMBL265046 | 0.84 | ATM (0.56) | HTTFOLH1CTRB1ATMCTSL | |
| SCHEMBL6605708 | 0.84 | CTRB1 (0.52) | HTTCTRB1ATMCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347354-A | Preparation of 1-N-[ω-amino-α-hydroxyalkanoyl]aminoglycoside polysilylated antibiotics and products obtained therefrom | BRISTOL-MYERS COMPANY (US) | 1982-08-31 | — | — | US | disclosed |