Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 5/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202368 | 0.93 | HTT (0.59) | HTTFOLH1CTRB1CASP1SLC1A3 | |
| SCHEMBL6941323 | 0.86 | CASP1 (0.56) | HTTCTRB1CASP1ATMCA12 | |
| SCHEMBL6937929 | 0.86 | CASP1 (0.56) | HTTCTRB1CASP1ATMCA12 | |
| SCHEMBL6200622 | 0.86 | CASP1 (0.56) | HTTCTRB1CASP1ATMCA12 | |
| Hydrochloric Acid SCHEMBL10636143 | 0.85 | CTSK (0.55) | CTRB1ATMCTSLTRPM8 | |
| SCHEMBL11255815 | 0.85 | HTT (0.56) | HTTFOLH1CTRB1CASP1MME | |
| SCHEMBL14625712 | 0.84 | CTRB1 (0.64) | CTRB1ATMCA12CA1CA2 | |
| SCHEMBL10953605 | 0.84 | CTRB1 (0.64) | CTRB1ATMCA12CA1CA2 | |
| SCHEMBL5501379 | 0.84 | CTSL (0.61) | CTRB1MMEECE1ATMCTSL | |
| SCHEMBL7976786 | 0.84 | CTRB1 (0.50) | HTTCTRB1SLC1A3SLC1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |