Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246032 | 0.87 | HRH3 (0.60) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL11252884 | 0.87 | LMNA (0.58) | LMNA | |
| SCHEMBL11253964 | 0.83 | SIGMAR1 (0.61) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL24163546 | 0.79 | KDM4E (0.70) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL11251231 | 0.79 | ALDH1A1 (0.60) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL11255661 | 0.79 | ALDH1A1 (0.62) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9075247 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL9078014 | 0.78 | HRH3 (0.54) | HRH3SIGMAR1 | |
| SCHEMBL17285907 | 0.76 | SIGMAR1 (0.74) | KDM4EALDH1A1LMNAHRH3SIGMAR1 | |
| SCHEMBL11248417 | 0.75 | ABCB1 (0.55) | KDM4EMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |