Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251231 | 0.90 | ALDH1A1 (0.60) | HRH3ALDH1A1LMNASIGMAR1MEN1 | |
| SCHEMBL11255661 | 0.87 | ALDH1A1 (0.62) | HRH3ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11253990 | 0.87 | L3MBTL1 (0.61) | HRH3ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL11253964 | 0.87 | SIGMAR1 (0.61) | HRH3ALDH1A1LMNASIGMAR1MEN1 | |
| SCHEMBL11255822 | 0.87 | KDM4E (0.59) | HRH3ALDH1A1LMNASIGMAR1MEN1 | |
| SCHEMBL11257123 | 0.86 | L3MBTL1 (0.60) | HRH3ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL11260526 | 0.85 | KDM4E (0.50) | HRH3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11258366 | 0.84 | HRH3 (0.50) | HRH3ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL11264264 | 0.84 | ABCB1 (0.53) | ALDH1A1KDM4EABCB1 | |
| SCHEMBL11248417 | 0.79 | ABCB1 (0.55) | SIGMAR1MEN1KMT2AKDM4EABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |