SCHEMBL11255979

SCHEMBL11255979

CCC1(c2ccccc2)OC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
TSHR P16473 2/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ADK P55263 1/20 0.43
LMNA P02545 1/20 0.41
MMP2 P08253 3/20 0.39
MMP9 P14780 3/20 0.39
CYP2C19 P33261 2/20 0.39
MMP3 P08254 2/20 0.39
HSD11B1 P28845 3/20 0.39
PTGER3 P43115 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11262329 0.86 MMP2 (0.42) HCAR3HCAR2TSHRMEN1CYP1A2
SCHEMBL11259531 0.81 HCAR3 (0.37) HCAR3HCAR2TSHRMEN1CYP1A2
SCHEMBL27771841 0.74 PTGER3 (0.43) HCAR3HCAR2TSHRMEN1POLB
SCHEMBL6237090 0.72 MMP2 (0.47) HCAR3HCAR2TSHRMEN1CYP1A2
SCHEMBL28341503 0.71 LMNA (0.41) HCAR3HCAR2MEN1POLBKMT2A
SCHEMBL11263455 0.71 PTGER3 (0.50) TSHRMEN1CYP1A2POLBAPEX1
SCHEMBL3098351 0.69 DRD2 (0.62) HCAR3HCAR2TSHRMEN1CYP1A2
SCHEMBL14752074 0.69 HCAR3 (0.48) HCAR3HCAR2TSHRMEN1CYP1A2
SCHEMBL28344049 0.67 LMNA (0.41) HCAR3HCAR2MEN1POLBKMT2A
SCHEMBL3107779 0.67 HCAR2 (1.00) HCAR3HCAR2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314023-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-02-02 US disclosed