SCHEMBL11262329

SCHEMBL11262329

CCCC1(c2ccccc2)OC(=O)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.42
MMP9 P14780 3/20 0.42
MMP3 P08254 1/20 0.42
HCAR3 P49019 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
APEX1 P27695 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38
DRD2 P14416 1/20 0.37
SIGMAR1 Q99720 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11255979 0.86 HCAR3 (0.50) MMP2MMP9MMP3HCAR3HCAR2
SCHEMBL28341503 0.81 LMNA (0.41) MMP2MMP9MMP3HCAR3HCAR2
SCHEMBL11259531 0.79 HCAR3 (0.37) MMP2MMP9MMP3HCAR3HCAR2
SCHEMBL29097003 0.72 HCAR3 (0.40) MMP2MMP9MMP3HCAR3HCAR2
SCHEMBL27771841 0.72 PTGER3 (0.43) HCAR3HCAR2KMT2AMEN1POLB
SCHEMBL6237090 0.69 MMP2 (0.47) MMP2MMP9HCAR3HCAR2KMT2A
SCHEMBL11413968 0.69 HCAR2 (0.78) HCAR3HCAR2CYP1A2
SCHEMBL11263455 0.69 PTGER3 (0.50) MMP2MMP9KMT2AMEN1CYP1A2
SCHEMBL3498871 0.66 HSD11B1 (0.32) LMNA
SCHEMBL28344049 0.65 LMNA (0.41) HCAR3HCAR2KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4314023-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-02-02 US disclosed