Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.63 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257246 | 1.00 | TACR1 (0.63) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL8750811 | 0.95 | TACR1 (0.60) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL8750802 | 0.95 | TACR1 (0.60) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL11232416 | 0.94 | ITGB3 (0.62) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL9483704 | 0.89 | MC4R (0.61) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL9483700 | 0.89 | MC4R (0.61) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL6349585 | 0.89 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL14305072 | 0.88 | TGM2 (0.54) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL6582593 | 0.87 | CYP2C19 (0.62) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL14790789 | 0.87 | P2RX7 (0.53) | TACR1P2RX7CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013790-B1 | CLAVULANIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |