Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750811 | 1.00 | TACR1 (0.60) | TACR1P2RX7ITGB3ITGA2BCTSL | |
| SCHEMBL11257246 | 0.95 | TACR1 (0.63) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL11257249 | 0.95 | TACR1 (0.63) | TACR1P2RX7CTSLCTSBCTSS | |
| SCHEMBL14305072 | 0.91 | TGM2 (0.54) | TACR1P2RX7ITGB3ITGA2BCTSL | |
| SCHEMBL11232416 | 0.89 | ITGB3 (0.62) | TACR1P2RX7ITGB3ITGA2BCTSL | |
| SCHEMBL25185922 | 0.86 | CASP1 (0.59) | CTSLCTSSCTSK | |
| SCHEMBL9003099 | 0.85 | CASP1 (0.58) | CTSK | |
| SCHEMBL9003092 | 0.85 | CASP1 (0.58) | CTSK | |
| SCHEMBL30054191 | 0.85 | CTSL (0.56) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7145151 | 0.85 | CASP1 (0.58) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |