Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11255774 | 0.86 | RAB9A (0.55) | CYP1A2CYP2C19RAB9ANPC1RECQL | |
| SCHEMBL11258085 | 0.83 | ALDH1A1 (0.44) | CYP1A2CYP2C19RAB9APKMGAA | |
| SCHEMBL11260181 | 0.81 | L3MBTL1 (0.42) | CYP1A2CYP2C19RAB9ANPC1RECQL | |
| SCHEMBL6900182 | 0.76 | RAB9A (0.42) | CYP1A2CYP2C19RAB9ANPC1RECQL | |
| SCHEMBL2795255 | 0.73 | MAPT (0.44) | CYP1A2CYP2C19RAB9ANPC1RECQL | |
| SCHEMBL11255665 | 0.71 | USP2 (0.45) | CYP1A2CYP2C19RAB9ANPC1GAA | |
| SCHEMBL11247772 | 0.70 | GAA (0.45) | CYP1A2CYP2C19PKMGAACASP3 | |
| SCHEMBL6558629 | 0.70 | LMNA (0.70) | RAB9ANPC1PKMGAACASP3 | |
| SCHEMBL1936827 | 0.69 | MAPT (0.47) | CYP1A2CYP2C19RAB9ANPC1KMT2A | |
| SCHEMBL5070268 | 0.68 | RAB9A (0.56) | CYP1A2CYP2C19RAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324892-A | 7-(N-Substituted-2-phenylglycinamido)-3-substituted-3-cephem-4-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-13 | — | — | US | disclosed |
| US-4172198-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-10-23 | — | — | US | disclosed |