Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213997 | 0.88 | KMT2A (0.33) | PDE5AKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL11183365 | 0.86 | POLB (0.38) | POLB | |
| SCHEMBL11199902 | 0.83 | SMN1; SMN2 (0.42) | PDE5AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11196868 | 0.81 | HTT (0.32) | LMNAHTT | |
| SCHEMBL11190490 | 0.68 | HTT (0.42) | KMT2AHTTPOLB | |
| SCHEMBL11222613 | 0.67 | POLB (0.42) | PDE5AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10942665 | 0.67 | SMN1; SMN2 (0.45) | KMT2ALMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10944369 | 0.67 | SMN1; SMN2 (0.45) | KMT2ALMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11199916 | 0.67 | SMN1; SMN2 (0.44) | PDE5AKMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL11186430 | 0.66 | ALDH1A1 (0.44) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |