Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.35 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.35 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089455 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL11095711 | 0.79 | CYP3A4 (0.40) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL11381103 | 0.78 | KCNA5 (0.40) | KCNA5KCNH2ALDH1A1KDM4EGAA | |
| SCHEMBL11093127 | 0.78 | MEN1 (0.34) | ALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL11090519 | 0.77 | CYP3A4 (0.34) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL11087533 | 0.77 | ALDH1A1 (0.37) | KCNA5KCNH2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11092419 | 0.77 | ALDH1A1 (0.41) | KCNA5KCNH2ALDH1A1GAAMAPT | |
| SCHEMBL11094159 | 0.74 | KCNA5 (0.44) | KCNA5KCNH2ALDH1A1HSD17B10GAA | |
| SCHEMBL11266308 | 0.74 | ALDH1A1 (0.34) | KCNA5KCNH2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11203944 | 0.68 | ALDH1A1 (0.42) | KCNA5ALDH1A1GAACYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337253-A | 4,5-Dihydro-2-methyl-6-(4-pyridinyl)-3(2H)-pyridazinone and its use as a cardiotonic | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |