Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649536 | 0.80 | TDP1 (0.59) | MAPTKDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23095360 | 0.79 | SLC6A3 (0.48) | MAPTKDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16735228 | 0.78 | PSMD14 (0.54) | PSMD14SLC40A1MAPTKDM4ETDP1 | |
| SCHEMBL70429 | 0.78 | LMNA (0.59) | PSMD14MAPTKDM4EALDH1A1POLB | |
| SCHEMBL11445824 | 0.77 | KDM4E (0.40) | MAPTKDM4ETDP1ATMMAPK1 | |
| SCHEMBL11265967 | 0.76 | ELANE (0.46) | MAPTKDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3230050 | 0.74 | NR4A2 (0.53) | PSMD14MAPTKDM4EALDH1A1POLB | |
| SCHEMBL69886 | 0.74 | PSMD14 (0.73) | PSMD14SLC40A1KDM4ETDP1ALDH1A1 | |
| SCHEMBL70381 | 0.74 | BRD4 (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29434198 | 0.74 | BRD4 (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |