Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 8/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.44 |
| ▸ | RIPK3 | Q9Y572 | 6/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270259 | 0.87 | ALDH1A1 (0.43) | KDM4E | |
| SCHEMBL11269173 | 0.79 | CLK1 (0.40) | CSNK1DMAPT | |
| SCHEMBL11254392 | 0.76 | SMN1; SMN2 (0.43) | CSNK1DMAPT | |
| SCHEMBL11261037 | 0.75 | MAPT (0.64) | CSNK1DKDM4EMAPT | |
| SCHEMBL11464906 | 0.72 | HTR1A (0.47) | MAPT | |
| SCHEMBL10758926 | 0.72 | HDAC1 (0.42) | KDM4E | |
| SCHEMBL11251039 | 0.71 | CLK1 (0.57) | KDM4EMAPT | |
| SCHEMBL6031383 | 0.71 | MITF (0.49) | MAPT | |
| SCHEMBL11383597 | 0.70 | HTR1A (0.47) | MAPT | |
| SCHEMBL11252930 | 0.68 | CLK1 (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |