Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 6/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254392 | 0.83 | SMN1; SMN2 (0.43) | CLK1ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL11270259 | 0.79 | ALDH1A1 (0.43) | CLK1GFERL3MBTL1ALDH1A1HTT | |
| SCHEMBL11261033 | 0.79 | CSNK1D (0.48) | MAPTCSNK1D | |
| SCHEMBL11251039 | 0.76 | CLK1 (0.57) | CLK1ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL11269176 | 0.73 | CLK1 (0.56) | CLK1ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL11252930 | 0.73 | CLK1 (0.41) | CLK1L3MBTL1ALDH1A1HTTPOLB | |
| SCHEMBL11256488 | 0.72 | ALDH1A1 (0.53) | CLK1L3MBTL1ALDH1A1HTTPOLB | |
| SCHEMBL11265296 | 0.71 | TERT (0.48) | CLK1ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL11265331 | 0.70 | KDM4E (0.62) | CLK1ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL11269060 | 0.70 | KMT2A (0.51) | CLK1L3MBTL1ALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |