Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CLK1 | P49759 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261033 | 0.87 | CSNK1D (0.48) | KDM4E | |
| SCHEMBL11254392 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2KMT2ACLK1MEN1 | |
| SCHEMBL11269173 | 0.79 | CLK1 (0.40) | ALDH1A1SMN1; SMN2LMNAKMT2ACLK1 | |
| SCHEMBL11261947 | 0.77 | DRD2 (0.54) | ALDH1A1KDM4ESMN1; SMN2TSHRSLC27A1 | |
| SCHEMBL11251039 | 0.77 | CLK1 (0.57) | ALDH1A1KDM4ESMN1; SMN2TSHRKMT2A | |
| SCHEMBL11252930 | 0.74 | CLK1 (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL6301700 | 0.72 | SIGMAR1 (0.42) | ALDH1A1KDM4EUSP2TSHRKMT2A | |
| SCHEMBL11270275 | 0.72 | SLC27A1 (0.69) | ALDH1A1SMN1; SMN2USP2LMNATSHR | |
| SCHEMBL11254394 | 0.72 | PKM (0.59) | CLK1L3MBTL1 | |
| SCHEMBL11255823 | 0.71 | HPGD (0.55) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |