Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261308 | 0.88 | L3MBTL1 (0.41) | POLBL3MBTL1MLYCDIDH1NLRP3 | |
| SCHEMBL11261924 | 0.85 | POLB (0.50) | POLBL3MBTL1MLYCDLMNAIDH1 | |
| SCHEMBL11263309 | 0.84 | MLYCD (0.44) | POLBL3MBTL1MLYCDLMNAIDH1 | |
| SCHEMBL11270933 | 0.83 | MLYCD (0.39) | MLYCDNR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL11263339 | 0.82 | POLB (0.47) | POLBL3MBTL1MLYCDLMNAIDH1 | |
| SCHEMBL11264342 | 0.82 | MLYCD (0.35) | MLYCDLMNANR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL11304409 | 0.79 | LMNA (0.40) | MLYCDLMNANLRP3NR1H3SMN1; SMN2 | |
| SCHEMBL11273420 | 0.77 | POLB (0.41) | POLBL3MBTL1MLYCDLMNAIDH1 | |
| SCHEMBL11263310 | 0.76 | L3MBTL1 (0.49) | POLBL3MBTL1MLYCDLMNAIDH1 | |
| SCHEMBL11267236 | 0.76 | NLRP3 (0.63) | POLBL3MBTL1LMNANLRP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |