Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271674 | 0.86 | POLB (0.43) | POLBLMNAMAPTMAPK1MEN1 | |
| SCHEMBL11267481 | 0.84 | LMNA (0.44) | LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11290903 | 0.82 | MAPT (0.53) | ABCB11LMNAMAPTMAPK1KDM4E | |
| SCHEMBL11265124 | 0.82 | ABCB11 (0.44) | CTDSP1ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11261344 | 0.80 | TSHR (0.46) | ABCB11LMNAMAPTMAPK1TSHR | |
| SCHEMBL11204042 | 0.78 | POLB (0.37) | POLBCTDSP1FPR2LMNAMAPT | |
| SCHEMBL11265051 | 0.77 | SMN1; SMN2 (0.51) | POLBGLAMEN1KMT2AALDH1A1 | |
| SCHEMBL11300097 | 0.75 | LMNA (0.49) | POLBFPR2ABCB11LMNAMAPT | |
| SCHEMBL11272380 | 0.75 | LMNA (0.54) | POLBCTDSP1ABCB11LMNAMAPT | |
| SCHEMBL11296990 | 0.75 | LMNA (0.39) | ABCB11LMNAMAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |